Serum osteocalcin levels compared with cervical maturational stages as growth indicators

OBJECTIVE: To determine whether serum osteocalcin levels can be used as a marker for assessing skeletal maturity. MATERIALS AND METHODS: The sample consisted of 60 patients aged 08-20 years (30 males, 30 females) reporting to Department Orthodontics and dentofacial orthopedics, Pedodontics ,Faculty dental sciences , Ramaiah university Applied Bangalore. Lateral cephalometric radiographs were obtained from all the subjects. Cervical staging orthodontic satisfying inclusion criteria evaluated on their respective lateral cephalograms by using Hassel Farman method. After cervical vertebral maturation evaluation, subjects selected study screened grouped into 6 stage (CS) groups 10 per group (5 5 females). 1ml blood was collected each patient after taking informed consent. centrifuged 20 min at room temperature then stored -20°C until analysis. samples subjected ELISA test determining Osteocalcin.